Vampire hunter, Maddie Sanders, moved to New York City to get away from her old life of killing the dead, but she finds that beyond the big city lights and hustle and bustle, lurks some of the deadliest demons the world has ever known.

After the crappiest first day in the Big Apple, Maddie  stakes a notorious vampire and accidentally breaks a 100-year-old treaty, pitting the bougie Upper East Side Vampire Brood and night dwelling Lower East Side Vampire Coven against each other for power over the city. Meanwhile, the unsuspecting humans of Crimson City are just trying to get through their 9 -5 daily grind.